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Job details
Job details
Job reference
19/107599
Date posted
01/07/2019
Application closing date
31/07/2019
Salary
£33,199 to £38,460 per annum
Job category/type
Research
Attachments
Blank
Research Fellow
Job description
The Centre for Experimental Medicine is an interdisciplinary research centre which is committed to the highest quality scientific endeavour, with over 250 basic and clinical scientists working on site. Our mission is to understand the mechanisms of disease and use that understanding to develop innovative new treatments and therapies to improve patient
outcomes.
We are recruiting for a highly productive, ambitious, creative and collaborative member of the research team led by Dr Karim Dib in the Centre for Experimental Medicine (CEM). The Research Fellow will work as part of an MRC-funded research programme that seeks to characterise the role of the histamine four receptor (H4R) in neutrophil phagocytosis. The project is aimed at investigating whether bacteria-derived histamine impairs human neutrophil phagocytosis by engaging the H4R on these leukocytes. We aim at investigating whether H4R antagonists may be used to improve bacterial clearance in the lungs of mice with cystic fibrosis (CF) by blocking the ability of histamine to impair neutrophil phagocytosis. We will utilise in vitro (human and murine neutrophils) and in vivo models (CF mouse model) to prove the role of the H4R in bacterial clearance. The described work will be carried out in collaboration with the group of Prof Miguel Valvano (CEM).
The Research Fellow will have responsibilities in independent research, supervision, planning, day-to-day lab management, collaborations and outreach.
This post is available until 30 November 2019 with possibility of extension.
Further information about the Centre and Dr Karim Dib can be found at:
https://www.qub.ac.uk/research-centres/wwiem/
https://pure.qub.ac.uk/portal/en/persons/karim-dib(d580b715-c115-467c-b526-4cd63e90ecf5).html
Informal enquiries may be directed to Dr Bettina Schock Email:
B.Schock@qub.ac.uk
Candidate Information
About the Centre
Further information for international applicants
Note to EEA applicants on Brexit
Job title
Research Fellow
Job reference
19/107599
Date posted
01/07/2019
Application closing date
31/07/2019
Salary
£33,199 to £38,460 per annum
Job category/type
Research
Attachments
Blank
Job description
The Centre for Experimental Medicine is an interdisciplinary research centre which is committed to the highest quality scientific endeavour, with over 250 basic and clinical scientists working on site. Our mission is to understand the mechanisms of disease and use that understanding to develop innovative new treatments and therapies to improve patient
outcomes.
We are recruiting for a highly productive, ambitious, creative and collaborative member of the research team led by Dr Karim Dib in the Centre for Experimental Medicine (CEM). The Research Fellow will work as part of an MRC-funded research programme that seeks to characterise the role of the histamine four receptor (H4R) in neutrophil phagocytosis. The project is aimed at investigating whether bacteria-derived histamine impairs human neutrophil phagocytosis by engaging the H4R on these leukocytes. We aim at investigating whether H4R antagonists may be used to improve bacterial clearance in the lungs of mice with cystic fibrosis (CF) by blocking the ability of histamine to impair neutrophil phagocytosis. We will utilise in vitro (human and murine neutrophils) and in vivo models (CF mouse model) to prove the role of the H4R in bacterial clearance. The described work will be carried out in collaboration with the group of Prof Miguel Valvano (CEM).
The Research Fellow will have responsibilities in independent research, supervision, planning, day-to-day lab management, collaborations and outreach.
This post is available until 30 November 2019 with possibility of extension.
Further information about the Centre and Dr Karim Dib can be found at:
https://www.qub.ac.uk/research-centres/wwiem/
https://pure.qub.ac.uk/portal/en/persons/karim-dib(d580b715-c115-467c-b526-4cd63e90ecf5).html
Informal enquiries may be directed to Dr Bettina Schock Email:
B.Schock@qub.ac.uk
Candidate Information
About the Centre
Further information for international applicants
Note to EEA applicants on Brexit